Childhood herpes simplex encephalitis (HSE): a novel primary immunodeficiency

Rebeca perez de diego

Nationality Spanish

Year of selection 2009

Institution Université Paris Descartes - Paris 5

Country France

Risk Health

Post-Doctoral Fellowship

2 years

105000 €

Could Genetics Explain Certain Viral Infections?

When a healthy child falls ill with a rare, life-¬threatening viral disease, could there be a genetic reason? Primary immunodeficiencies (PIDs) are genetic disorders that leave a person susceptible to infections. A new kind of PID may play a role specifically in herpes simplex virus encephalitis, a terrible infection of the central nervous system. Dr. Rebeca Pérez de Diego aims to identify new PIDs that may be responsible—work that could lead to treatments restoring these children’s missing immune function.

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